Dual responsive supramolecular nanogels for intracellular drug delivery.

نویسندگان

  • Xiaofei Chen
  • Li Chen
  • Xuemei Yao
  • Zhe Zhang
  • Chaoliang He
  • Jingping Zhang
  • Xuesi Chen
چکیده

Supramolecular nanogels cross-linked by host-guest interaction between dextran grafted benzimidazole (Dex-g-BM) and thiol-β-cyclodextrin were designed. Their special supramolecular pH-sensitivity under acidic conditions (pH < 6, within the range of malignant cellular endosomes) and reduction sensitivity in response to biologically relevant stimuli will be of great advantage to the future of cancer chemotherapeutics.

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عنوان ژورنال:
  • Chemical communications

دوره 50 29  شماره 

صفحات  -

تاریخ انتشار 2014